Due to each country’s health regulation, laws and consumer protection, Invel has either, registered in the Federal Regulatory Agencies in some countries, notified or followed an existing health category policy. It means that, a country statement is not validated in other countries, because of the costume, culture, population and consumer rights. The clinical trials were approved by an independent ethics committee (IEC), informed consent from the subjects and Invel products are manufactured under the Good Manufacturing Practice (GMPs).